Biologically Active Glycosides from Asteroidea, 42. Isolation and Structure of a New Biologically Active Ganglioside Molecular Species from the Starfish Asterina pectinifera

Constituents of holothuroidea. 10. Isolation and structure of a biologically active ganglioside molecular species from the sea cucumber Holothuria leucospilota.

Three ganglioside molecular species, HLG-1 (1), HLG-2 (2), and HLG-3 (3) have been obtained from the lipid fraction of the chloroform/methanol extract of the sea cucumber Holothuria leucospilota. The structures of these gangliosides have been determined, on the basis of chemical and spectroscopic evidence, as 1-O-[(N-glycolyl-alpha-D-neuraminosyl)-(2-->6)-beta-D-glucopyranosyl]-ceramide (1), 1-...

Isolation of biologically active Actinomycetes from untouched soils: a case study from Karaj district, Iran

Actinomycetes are a source of a broad variety of secondary metabolites with diverse biological activities, such as antifungi, antibiotics and antitumorals; many of which have been developed for clinical use. In this study, 34 actinomycetes from untouched soils were isolated from Alborz Province-Iran. Evaluation ofantifungal and anti bacterial activities of these isolates, demonstrated the capab...

Biologically Active Sesterterpenes from a New Caledonian

Chemical investigations of marine sponges from the genus Hyrtios has yielded a predominance of scalarane-type sesterterpenes.' We have previously isolated heteronemin and the new 12-epi-heteronemin as representatives of this class of sesterterpenes, from the marine sponge Hyrtìos erecta collected in New Caledonia? However, both scalarane-type sesterterpenes and those of the manoalide family hav...

Isolation and characteristics of trypsin from pyloric ceca of the starfish Asterina pectinifera.

Trypsin was purified from pyloric ceca of the starfish Asterina Pectinifera by ammonium sulfate precipitation, gel filtration, and cation-exchange chromatography. Final enzyme preparation was nearly homogeneous in sodium dodecyl sulfate-polyacrylamide gel electrophoresis and its molecular weight was estimated as approximately 28000. Optimum pH and temperature of A. pectinifera trypsin for hydro...

Isolation and characteristics of phospholipase A2 from the pyloric ceca of the starfish Asterina pectinifera